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產品名稱：重組小鼠CD33(Siglec-3)
英文名稱：Recombinant Mouse Sialic Acid Binding Ig-like Lectin 3
產品貨號：JN1892
產品規(guī)格：10μg|50μg|500μg|1mg

本品由我們的哺乳動物細胞表達系統(tǒng)制備而成，目的基因編碼的Asp18-Glu240在C端含有His標簽。

CD33/Siglec-3質量控制：＞95%(還原性SDS-PAGE)

CD33/Siglec-3制劑：凍干品

CD33/Siglec-3保存：
凍干蛋白置于-20℃以下可長期保存，室溫條件下可穩(wěn)定保存3周。
復溶蛋白溶液可在4～7℃保存2～7天，可分裝后置于-20℃保存三個月。

CD33/Siglec-3復溶：
打開試劑管前請先離心。
復溶濃度推薦大于100 μg/ml。
凍干蛋白請溶于ddH2O。
復溶后，請根據用量分裝凍存，避免反復凍融。

關于CD33/Siglec-3：
Mouse myeloid cell surface antigen CD33(CD33) is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. CD33 contains one Ig-like C2-type domain and one Ig-like V-type domain. CD33 is a putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. CD33 preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, CD33 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. CD33 induces apoptosis in acute myeloid leukemia. CD33 is becoming increasingly important as a target of antibody-mediated therapy in acute myeloid leukaemia (AML).

根據您的關注的重組小鼠CD33(Siglec-3)，rSiglec-3，rmSiglec-3，重組小鼠CD33，重組小鼠Siglec-3，重組Siglec-3，Recombinant Mouse Sialic Acid Binding Ig-like Lectin 3，rmCD33，重組小鼠Sialic Acid Binding Ig-like Lectin 3，重組Sialic Acid Binding Ig-like Lectin 3，重組CD33，rCD33，您可能還對以下產品有需求：



名稱：重組小鼠血小板生成素
貨號：JN0279
規(guī)格：10μg|50μg|500μg|1mg
本品由我們的哺乳動物表達系統(tǒng)制備，目的基因編碼的Ser22­Thr356在N端含有His標簽

Thrombopoietin/TPO質量控制：＞95%(還原性SDS-PAGE)。

Thrombopoietin/TPO制劑：凍干品

Thrombopoietin/TPO保存：
凍干蛋白可在-20℃長期保存，室溫也可穩(wěn)定保存3周。
復溶蛋白溶液可在4～7℃保存2～7天。
復溶后建議分裝凍存在-20℃，可保存3個月，應避免反復凍融。

Thrombopoietin/TPO復溶：
1、試劑開蓋前請先離心。
2、復溶濃度應大于100 μg/ml.
3、凍干蛋白溶于ddH2O中
4、復溶后根據使用量分裝保存，避免反復凍融。

關于Thrombopoietin/TPO：
Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets.Mature mouse Tpo shares 71% and 81% aa sequence homology with human and rat Tpo, respectively. It is an 80-85 kDa protein that consists of an N-terminal domain with homology to Erythropoietin (Epo) and a C-terminal domain that contains multiple N-linked and O-linked glycosylation sites. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. Lineage-specific cytokine affects the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.

關注重組小鼠CD33(Siglec-3)，rSiglec-3，rmSiglec-3，重組小鼠CD33，重組小鼠Siglec-3，重組Siglec-3，Recombinant Mouse Sialic Acid Binding Ig-like Lectin 3，rmCD33，重組小鼠Sialic Acid Binding Ig-like Lectin 3，重組Sialic Acid Binding Ig-like Lectin 3，重組CD33，rCD33的同時，為您推薦更多您可能感興趣的產品：


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